{"id":11836,"date":"2025-06-06T10:05:52","date_gmt":"2025-06-06T08:05:52","guid":{"rendered":"https:\/\/marie-notre-etoile.org\/?p=11836"},"modified":"2025-06-06T10:22:57","modified_gmt":"2025-06-06T08:22:57","slug":"de-nouvelles-molecules","status":"publish","type":"post","link":"https:\/\/marie-notre-etoile.org\/en\/de-nouvelles-molecules\/","title":{"rendered":"New molecules"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"11836\" class=\"elementor elementor-11836\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d53a177 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d53a177\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-09bb2f8\" data-id=\"09bb2f8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-fd3770d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fd3770d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d05da74\" data-id=\"d05da74\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9b578de elementor-widget elementor-widget-image\" data-id=\"9b578de\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"210\" src=\"https:\/\/marie-notre-etoile.org\/wp-content\/uploads\/2025\/06\/molecule-300x210.png\" class=\"attachment-medium size-medium wp-image-11842\" alt=\"Mol\u00e9cule sch\u00e9matique symbolisant une avanc\u00e9e pour mieux combattre le cancer par l&apos;Institut Curie, du CNRS et de l\u2019Inserm.\" srcset=\"https:\/\/marie-notre-etoile.org\/wp-content\/uploads\/2025\/06\/molecule-300x210.png 300w, https:\/\/marie-notre-etoile.org\/wp-content\/uploads\/2025\/06\/molecule-18x12.png 18w, https:\/\/marie-notre-etoile.org\/wp-content\/uploads\/2025\/06\/molecule.png 492w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8efb681\" data-id=\"8efb681\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8497b24 elementor-widget elementor-widget-heading\" data-id=\"8497b24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A promising step forward to better combat cancer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-75794c4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"75794c4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0bc06df\" data-id=\"0bc06df\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ca0cf6f elementor-widget elementor-widget-text-editor\" data-id=\"ca0cf6f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Researchers at the<strong>Institut Curie<\/strong>, <strong>CNRS<\/strong> and <strong>Inserm<\/strong> have developed a new class of molecules capable of causing the death of cancer cells resistant to conventional treatments. This discovery, published in the journal Nature, opens up encouraging prospects for fighting the most aggressive forms of cancer.<\/p><p><b><br \/>Understand Discovery<\/b><\/p><p>Some cancer cells, called \u201cpersistent\u201d cells, survive conventional treatments and are often responsible for recurrences and metastases. These cells have a high concentration of CD44 protein, which allows them to absorb more iron, making them more aggressive and resistant.<br \/>The researchers designed a molecule, fentomycin (Fento-1), which specifically targets these cells by activating the iron they store. This activation triggers a chain reaction, called ferroptose, which damages cell membranes and leads to cell death.<\/p><p><b>Why could this discovery help children with cancer?<\/b><\/p><p>Research could pave the way for new approaches against the most aggressive or tenacious tumors, including in children.<br \/>With <strong>Marie Notre \u00c9toile<\/strong>, we believe that every scientific advance is a small light of hope. Because what is true today for one type of cancer can, tomorrow, become a track for others. Searching is a long way, but every step counts. Thank you to the researchers, but also to the donors who make this progress possible!<\/p><p>Learn more about this discovery as well as early findings: <a href=\"https:\/\/www.nature.com\/articles\/s41586-025-08974-4\" target=\"_blank\" rel=\"noopener\">Read the article on the Nature website<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>A discovery published by the Institut Curie, the CNRS and the Inserm in the journal Nature on May 7, 2025 reveals new treatments.<\/p>","protected":false},"author":2,"featured_media":11842,"comment_status":"closed","ping_status":"open","sticky":false,"template":"elementor_theme","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[32,58],"tags":[53],"class_list":["post-11836","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medias-all","category-news-2025","tag-annee-2024"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"Une avanc\u00e9e prometteuse pour mieux combattre le cancer Les chercheurs de l\u2019Institut Curie, du CNRS et de l\u2019Inserm ont mis au point une nouvelle classe de mol\u00e9cules capables de provoquer la mort des cellules canc\u00e9reuses r\u00e9sistantes aux traitements conventionnels. Cette d\u00e9couverte, publi\u00e9e dans la revue Nature le 7 mai 2025, ouvre des perspectives encourageantes pour\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Thomas Delaloy\"\/>\n\t<meta name=\"google-site-verification\" content=\"7Ch0h4uqMac7-F-Akd2JkDWIk4oOBl75eOGQCy0jUDI\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/marie-notre-etoile.org\/en\/de-nouvelles-molecules\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.9\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Marie Notre Etoile - Soutenons la recherche scientifique contre le cancer des enfants\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"De nouvelles mol\u00e9cules - Marie Notre Etoile\" \/>\n\t\t<meta property=\"og:description\" content=\"Une avanc\u00e9e prometteuse pour mieux combattre le cancer Les chercheurs de l\u2019Institut Curie, du CNRS et de l\u2019Inserm ont mis au point une nouvelle classe de mol\u00e9cules capables de provoquer la mort des cellules canc\u00e9reuses r\u00e9sistantes aux traitements conventionnels. 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